      
      GLP-1 Treatments
    

Compounded GLP-1s for
Clinically Supervised Weight Loss

Clinically proven GLP-1 receptor agonists like semaglutide and tirzepatide, prescribed by licensed providers after your consultation.

Start Your Protocol Learn How It Works

Clinical data

15–22%

        Average body weight reduction in clinical studies
      

$249

        Starting monthly — vs. $1,000+ brand name
      

503A

        Licensed pharmacy — FDA-registered APIs
      

        GLP-1 Pharmacology
      

How GLP-1 Agonists Actually Work

These aren't appetite suppressants. GLP-1 receptor agonists are synthetic analogs of an endogenous incretin hormone that acts on multiple organ systems simultaneously — gut, brain, pancreas, and liver.

          Gastric Emptying
        

Slows the rate at which food leaves the stomach by ~30–50%. This prolongs satiety signaling to the brain via vagal afferent nerves — not by "shrinking" your stomach, but by delaying nutrient delivery to the duodenum.

          Hypothalamic Action
        

GLP-1 receptors in the arcuate nucleus of the hypothalamus directly suppress appetite via POMC/CART neuron activation while inhibiting NPY/AgRP hunger pathways. This is central, not peripheral appetite control.

          Insulinotropic Effect
        

Glucose-dependent insulin secretion from pancreatic β-cells — meaning GLP-1s only stimulate insulin release when blood glucose is elevated, virtually eliminating hypoglycemia risk. Simultaneously suppresses glucagon.

          Clinical Endpoint
        

15–24% Body Weight Reduction

Range across semaglutide STEP trials (14.9%) to tirzepatide SURMOUNT-1 (22.5%) at 48–72 weeks. Brand-name equivalents cost $1,000+/month; compounded versions $249–399/month.

          Safety Profile
        

Well-Characterized After 20+ Years

GLP-1s have been prescribed since 2005 (exenatide). Most side effects are GI-related (nausea, constipation) and transient — typically resolving within 4 weeks of dose escalation. Serious risks (pancreatitis, thyroid C-cell tumors) are rare and screened for during intake.

        GLP-1 Formulary
      

Compounded GLP-1 Medications

Every GLP-1 is compounded at our 503A-licensed pharmacy using FDA-registered APIs. Your provider selects the right medication and dose-escalation schedule based on your intake, labs, and goals.

GLP-1 Agonist

Semaglutide

          Brand: Ozempic® / Wegovy®
        

The most widely studied GLP-1 agonist. Semaglutide has 94% sequence homology to native human GLP-1 with two key modifications: an albumin-binding fatty acid chain (extending half-life to ~7 days) and a substitution at position 8 to resist DPP-4 degradation. STEP trial data: 14.9% mean body weight reduction at 68 weeks vs 2.4% placebo.

Once-Weekly ~15% Weight Loss FDA Approved 2021 CV Benefit

$249

          /month
        

1 Month — $249 2 Months — $229/mo Best Value3 Months — $199/mo

Best Results

Dual GIP/GLP-1

Tirzepatide

          Brand: Mounjaro® / Zepbound®
        

First-in-class dual agonist: a 39-amino-acid synthetic peptide that agonizes both GLP-1 and GIP receptors — the latter enhancing insulin sensitivity independently. SURMOUNT-1 showed 22.5% mean weight loss at 72 weeks (highest dose). GIP agonism also appears to mitigate GI side effects compared to pure GLP-1s, improving tolerability during dose escalation.

Once-Weekly ~22% Weight Loss Dual Mechanism Better Tolerability

$399

          /month
        

1 Month — $399 2 Months — $369/mo Best Value3 Months — $329/mo

All GLP-1s compounded at FDA-registered 503A pharmacy • Provider prescription required after intake • Cold-chain shipped • Dose escalation managed by your provider

Who Is a Candidate?

GLP-1 medications may be right for you if:

BMI of 30 or greater (obesity), or BMI of 27+ with weight-related health conditions
Have not had success with diet and exercise alone
Are committed to lifestyle changes alongside medication
Do not have a history of certain medical conditions (thyroid cancer, pancreatitis)

Potential Side Effects

Common side effects are usually mild and improve over time:

Nausea, vomiting, or diarrhea (especially when starting)
Constipation or stomach pain
Headache or fatigue
Injection site reactions

Important: Your provider will review your complete medical history to ensure GLP-1 therapy is safe for you.

    Semaglutide from $249/mo · Tirzepatide from $399/mo
  

Your Provider Will Choose
the Right GLP-1

Complete your intake — a licensed provider reviews your health history and recommends the optimal medication and dosing schedule based on your specific goals, labs, and metabolic profile.

Start Your Protocol View Pricing